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We absolutely need to see data, but long imperfect reads are fine for de novo assembly, if you combine them with short lower error reads (Illumina or Ion Torrent). This combined approach is straightforward & what’s being done with PacBio data. I know Oxford would rather users relied upon their data entirely, but why not start with something that’s an immediate help to many of us & could let us stop making mate-pair libraries evermore?
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